Cellular Senescence Network (SenNet): Discovery, Validation Centers (UM1 Clinical Trials Not Allowed)
Grants.gov RFA-RM-27-016 · HHS-NIH11
| Funder | National Institutes of Health |
|---|---|
| Status | open |
| Opens | 09 Oct 2026 |
| Deadline | 23 Nov 2026 — 24 days |
| Action | posted |
| Official page | https://www.grants.gov/search-results-detail/359169… |
| Last checked | 2026-10-30 06:02:42+00:00 |
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The purpose of this Notice of Funding Opportunity (NOFO) is to support SenNet Discovery and Validation Centers (SenNet DVCs) as a core component of Stage 2 of the NIH Common Fund Cellular Senescence Network (SenNet). Building on Stage 1 resources, DVCs will define, refine, and validate tissue- and disease-relevant cellular senescence signatures (“senotypes”) and associated biomarkers, and will investigate their functional consequences in human health and disease. DVCs are expected to generate and contribute high-quality molecular, cellular, and spatial datasets (including relevant metadata and documentation) and to use complementary experimental systems, as appropriate, to validate senotypes/biomarkers and characterize responses to senescence-associated perturbations or senotherapeutic approaches. DVC applications should also propose goals and aims for SenNet consortium-wide organizational and outreach activities (SenNet OOC functions).
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